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Elobixibat - Albireo Pharma/EA Pharma

Drug Profile

Elobixibat - Albireo Pharma/EA Pharma

Alternative Names: A-3309; AJG-533; Goofice

Latest Information Update: 09 Apr 2021

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At a glance

  • Originator AstraZeneca
  • Developer Albireo Pharma; EA Pharma; Mochida Pharmaceutical; Yokohama City University
  • Class 2 ring heterocyclic compounds; Amides; Antihyperlipidaemics; Carboxylic acids; Hepatoprotectants; Irritable bowel syndrome therapies; Laxatives; Small molecules; Sulfides; Sulfones; Thiazepines
  • Mechanism of Action Sodium-bile acid cotransporter inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Constipation
  • Phase II Non-alcoholic fatty liver disease
  • Discontinued Dyslipidaemias; Irritable bowel syndrome; Non-alcoholic steatohepatitis

Most Recent Events

  • 31 Dec 2020 Albireo Pharma has patent protection and patents pending for elobixibat in US, Japan, Australia and Europe before December 2020
  • 31 Dec 2020 Adverse events data from phase III Echo-1 and Echo-2 trial in Constipation released by Albireo Pharma
  • 18 Aug 2020 Discontinued - Phase-II for Non-alcoholic steatohepatitis (Combination therapy) in Japan (PO)
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