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Patidegib - Sol-Gel Technologies

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Drug Profile

Patidegib - Sol-Gel Technologies

Alternative Names: BBP-009; FIN-5; IPI-926; Patidegib topical gel - PellePharm; Patidegib-hydrochloride; Saridegib; Saridegib-hydrochloride; SGT-610

Latest Information Update: 18 Jul 2024

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At a glance

  • Originator Infinity Pharmaceuticals
  • Developer Infinity Pharmaceuticals; PellePharm; Sol-Gel Technologies
  • Class Antineoplastics; Naphthols; Pyridines; Small molecules; Spiro compounds; Sulfonamides; Veratrum alkaloids
  • Mechanism of Action SMO protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Basal cell nevus syndrome; Chondrosarcoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Basal cell nevus syndrome
  • Phase II Basal cell cancer
  • Discontinued Chondrosarcoma; Head and neck cancer; Myelofibrosis; Pancreatic cancer

Most Recent Events

  • 17 Mar 2024 Phase-III clinical trials in Basal Cell Nevus Syndrome in Poland (Topical) (NCT06050122)
  • 30 Nov 2023 Sol-Gel Technologies initiates enrolment in a phase III trial for Basal Cell Nevus Syndrome in USA, France, Germany, Netherlands, Spain, Italy and UK (Topical) (NCT06050122)
  • 28 Sep 2023 Infinity Pharmaceuticals files for Chapter 11 bankruptcy and has been dissolved

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