Patidegib - PellePharm

Drug Profile

Patidegib - PellePharm

Alternative Names: FIN-5; IPI-926; Patidegib topical gel - PellePharm; Patidegib-hydrochloride; Saridegib; Saridegib-hydrochloride

Latest Information Update: 14 Dec 2017

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At a glance

  • Originator Infinity Pharmaceuticals
  • Developer Infinity Pharmaceuticals; PellePharm
  • Class Antineoplastics; Small molecules; Veratrum alkaloids
  • Mechanism of Action SMO protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chondrosarcoma; Basal cell nevus syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Basal cell cancer; Basal cell nevus syndrome
  • Discontinued Chondrosarcoma; Head and neck cancer; Myelofibrosis; Pancreatic cancer

Most Recent Events

  • 20 Nov 2017 Patidegib receives Breakthrough Therapy status for Basal Cell Nevus Syndrome in USA
  • 20 Nov 2017 Patidegib receives Orphan Drug status for Basal Cell Nevus Syndrome in USA
  • 20 Nov 2017 PellePharm plans a phase III trial in Basal Cell Nevus Syndrome in USA in the first half of 2018
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