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RGRN 305

Drug Profile

RGRN 305

Alternative Names: BEBT-305; CU-0305; CUDC-305; DEBIO 0932; Debio-0932; MC2-32; RGRN-305

Latest Information Update: 02 Jan 2024

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At a glance

  • Originator Curis
  • Developer Curis; Debiopharm; MC2 Therapeutics; Regranion
  • Class 2 ring heterocyclic compounds; Anti-inflammatories; Antipsoriatics; Benzodioxoles; Imidazoles; Pyridines; Skin disorder therapies; Small molecules
  • Mechanism of Action HSP90 heat-shock protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hidradenitis suppurativa
  • Phase I Plaque psoriasis
  • Phase Unknown Atopic dermatitis; Bullous pemphigoid
  • Discontinued Cancer; Lymphoma; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours

Most Recent Events

  • 11 Oct 2023 Phase-II clinical trials in Hidradenitis suppurativa in Denmark (PO) before October 2023
  • 11 Oct 2023 MC2 Therapeutics plans a phase IIb trial for Hidradenitis suppurativa
  • 11 Oct 2023 Efficacy and adverse events data from a phase I trial in Hidradenitis suppurativa released by MC2 Therapeutics
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