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Icomidocholic acid - Galmed Pharmaceuticals

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Drug Profile

Icomidocholic acid - Galmed Pharmaceuticals

Alternative Names: Arachidyl amido cholanoic acid; Arachidyl amido cholanoic acid - Galmed Pharmaceuticals; Aramchol; Aramchol - Galmed Pharmaceuticals; Aramchol meglumine - Galmed Pharmaceuticals

Latest Information Update: 04 Oct 2024

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At a glance

  • Originator Galmed Medical Research
  • Developer Galmed Medical Research; Galmed Pharmaceuticals; University of California, San Diego
  • Class Anti-inflammatories; Antifibrotics; Bile acids and salts; Cholic acids; Drug conjugates; Eicosanoic acids; Eicosanoids; Fatty acids; Gallstone therapies; Hepatoprotectants; Small molecules
  • Mechanism of Action Stearoyl-CoA desaturase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Lipodystrophy; Non-alcoholic steatohepatitis

Highest Development Phases

  • Phase III Fibrosis; Non-alcoholic steatohepatitis
  • Phase II Cholelithiasis; Lipodystrophy; Non-alcoholic fatty liver disease
  • Preclinical Inflammatory bowel diseases

Most Recent Events

  • 19 Sep 2024 Galmed Pharmaceuticals terminated a phase II trial prior to enrollment in Primary sclerosing cholangitis in the US (NCT06095986)
  • 19 Sep 2024 Galmed Pharmaceuticals plans to expand to two additional programs for Liver cancer, Colorectal cancer, Glioma and Cardiovascular disorders
  • 17 Jul 2024 Galmed Pharmaceuticals plans a phase I pharmacokinetics trial in Healthy volunteers in Bulgaria (PO) (NCT06502561)

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