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Diazoxide choline controlled release - Soleno Therapeutics

Drug Profile

Diazoxide choline controlled release - Soleno Therapeutics

Alternative Names: DCCR; DCCR - Soleno Therapeutics; Diazoxide choline; Diazoxide choline controlled release; Diazoxide-choline-controlled-release-Essentialis

Latest Information Update: 06 Nov 2018

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At a glance

  • Originator Essentialis
  • Developer Essentialis; Soleno Therapeutics
  • Class Antihypertensives; Antihypoglycaemics; Benzothiadiazines; Diagnostic agents; Peripheral vasodilators; Small molecules
  • Mechanism of Action Potassium channel agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Prader-Willi syndrome
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Prader-Willi syndrome
  • No development reported Hypertriglyceridaemia
  • Discontinued Hypoglycaemia; Obesity

Most Recent Events

  • 01 Oct 2018 Soleno Therapeutics initiates enrolment in an open-label extension phase III trial for Prader-Willi syndrome (In adolescents, In adults, In children) in USA (NCT03714373)
  • 01 Oct 2018 Pharmacokinetics and efficacy data from five clinical trials in Prader-Willi syndrome released by Soleno Therapeutics
  • 06 Sep 2018 Soleno Therapeutics receives protocol amendment from the US FDA for the phase III DESTINY PWS trial for Prader-Willi syndrome
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