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Obicetrapib - NewAmsterdam Pharma

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Drug Profile

Obicetrapib - NewAmsterdam Pharma

Alternative Names: AMG 899; DEZ 001; obicetripib; TA-8995

Latest Information Update: 05 Aug 2025

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At a glance

  • Originator Mitsubishi Tanabe Pharma Corporation
  • Developer Amgen; Mitsubishi Tanabe Pharma Corporation; NewAmsterdam Pharma
  • Class Antidementias; Antihyperlipidaemics; Heterocyclic compounds; Quinolines; Small molecules
  • Mechanism of Action Cholesterol ester transfer protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Dyslipidaemias; Hyperlipoproteinaemia type IIa
  • Phase II Alzheimer's disease; Hypercholesterolaemia

Most Recent Events

  • 30 Jul 2025 Final pharmacodynamics data from the prespecified Alzheimer’s disease biomarker analysis in the phase III BROADWAY trial in Dyslipidaemias released by NewAmsterdam Pharma
  • 30 Jul 2025 Updated safety data from a phase IIa trial in Alzheimer's disease released by NewAmsterdam Pharma
  • 09 Jun 2025 Adverse events and efficacy data from the the phase-III BROADWAY trial in Dyslipidaemias released by NewAmsterdam Pharma

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