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Obicetrapib - NewAmsterdam Pharma

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Drug Profile

Obicetrapib - NewAmsterdam Pharma

Alternative Names: AMG 899; DEZ 001; obicetripib; TA-8995

Latest Information Update: 11 Dec 2025

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At a glance

  • Originator Mitsubishi Tanabe Pharma Corporation
  • Developer Amgen; Menarini; Mitsubishi Tanabe Pharma Corporation; NewAmsterdam Pharma
  • Class Antidementias; Antihyperlipidaemics; Heterocyclic compounds; Quinolines; Small molecules
  • Mechanism of Action Cholesterol ester transfer protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preregistration Dyslipidaemias; Hypercholesterolaemia
  • Phase III Hyperlipoproteinaemia type IIa
  • Phase II Alzheimer's disease

Most Recent Events

  • 01 Dec 2025 Mitsubishi Tanabe Pharma Corporation is now called Tanabe Pharma Corporation
  • 27 Oct 2025 NewAmsterdam Pharma plans the phase III RUBENS trial in Metabolic syndrome and Type 2 diabetes mellitus (PO), in December 2025(NCT07219602)
  • 18 Aug 2025 Preregistration for Dyslipidaemias (Adjunctive treatment) in European Union (PO)

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