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Tavokinogene telseplasmid - OncoSec Medical

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Drug Profile

Tavokinogene telseplasmid - OncoSec Medical

Alternative Names: 12-NGVL331; DNA IL-12; IL-12 gene therapy; IL-12 plasmid; IL-12-gene-therapy-Inovio; Immunopulse; ImmunoPulse; ImmunoPulse®IL-12; Interleukin-12 gene therapy; intratumoral pIL-12-EP; LipoVIL12; OMS ElectroImmunotherapy™; pIL-12; pIL-12 Electroporation; Plasmid-based interleukin-12 or pIL-12; pUMVC3-hIL; Tavo-EP; TAVOPLUS; Tavo™

Latest Information Update: 24 Jun 2024

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At a glance

  • Originator Inovio Biomedical Corporation
  • Developer Fred Hutchinson Cancer Research Center; H. Lee Moffitt Cancer Center and Research Institute; Massachusetts General Hospital; Merck Sharp & Dohme; OncoSec Medical; University of California at San Francisco; University of Washington
  • Class Antineoplastics; Cytokine genes; Gene therapies; Immunotherapies; Interleukins
  • Mechanism of Action Gene transference; Immunostimulants; Interleukin 12 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malignant melanoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Cutaneous T-cell lymphoma; Head and neck cancer; Malignant melanoma; Merkel cell carcinoma; Triple negative breast cancer
  • No development reported Solid tumours

Most Recent Events

  • 05 Apr 2024 Pharmacodynamics data from a phase II trial in Malignant melanoma presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 16 May 2023 OncoSec Medical plans a phase II trial for Neoadjuvant melanoma (Neoadjuvant therpay, Combination therapy)
  • 15 May 2023 OncoSec Medical completes Type C meeting with the US FDA

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