Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?


Drug Profile


Alternative Names: ALKS 33; RDC-0313; RDC-0313-00

Latest Information Update: 13 Nov 2019

Price : $50 *
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Rensselaer Polytechnic Institute
  • Developer Alkermes; Alkermes plc
  • Class Amides; Cyclopropanes; Drug withdrawal therapies; Morphinans; Small molecules
  • Mechanism of Action Opioid mu receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Alcoholism; CNS disorders; Eating disorders; Substance-related disorders

Most Recent Events

  • 07 Nov 2019 Ad-hoc task: Indication change from Drug abuse to Substance-related disorders - replaced the indication Drug abuse with Substance-related disorders in the Intro and HEs
  • 17 Dec 2015 No development reported - Phase-I for CNS disorders (In volunteers) in USA (PO)
  • 17 Dec 2015 No development reported - Phase-I for Substance-related disorders (In volunteers) in USA (PO)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top