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Promethazine/hydrocodone/paracetamol - Charleston Laboratories

Drug Profile

Promethazine/hydrocodone/paracetamol - Charleston Laboratories

Alternative Names: CL-108; HYDEXOR; Hydrocodone/paracetamol/promethazine; Paracetamol/promethazine/hydrocodone

Latest Information Update: 15 Jan 2019

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At a glance

  • Originator Charleston Laboratories
  • Class Acetanilides; Aminophenols; Antiallergics; Antiemetics; Antipyretics; Antitussives; Hypnosedatives; Morphinans; Non-opioid analgesics; Opioid analgesics; Opioid peptides; Propylamines; Sedating antihistamines
  • Mechanism of Action Histamine H1 receptor antagonists; Muscarinic receptor antagonists; Opioid receptor agonists; Prostaglandin receptor antagonists; Serotonin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preregistration Acute pain; Nausea and vomiting

Most Recent Events

  • 12 Sep 2018 Efficacy data from a phase II trial in Acute pain and Nausea and vomiting presented at the World Congress on Pain (WCP-2018)
  • 01 Aug 2018 Chemical structure information added
  • 01 Aug 2018 Phase-III clinical trials in Acute pain in USA (PO, Tablet, 12.5mg/10mg/325mg) (Charleston Laboratories pipeline, August 2018)
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