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Briquilimab - Jasper Therapeutics

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Drug Profile

Briquilimab - Jasper Therapeutics

Alternative Names: AMG-191; JSP-191

Latest Information Update: 27 Aug 2025

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At a glance

  • Originator Amgen; National Heart, Lung and Blood Institute; Stanford University
  • Developer Amgen; Jasper Therapeutics; Tectonic Therapeutic
  • Class Anti-inflammatories; Antiallergics; Antianaemics; Antineoplastics; Immunotherapies; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Proto-oncogene protein c-kit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Chronic urticaria
  • Phase I Allergic asthma; Myelodysplastic syndromes
  • Preclinical Anaphylaxis; Atopic dermatitis; Fabry's disease; Gaucher's disease
  • Discontinued Inflammation

Most Recent Events

  • 18 Aug 2025 Updated efficacy data from the phase Ib/IIa BEACON trial for Chronic urticaria released by Jasper Therapeutics
  • 09 Jul 2025 Jasper Therapeutics suspends a phase-I trial in Allergic asthma in Canada (SC) (NCT06592768)
  • 14 Jun 2025 Efficacy and adverse events data from the phase Ib/IIa SPOTLIGHT study in Chronic urticaria released by Jasper Therapeutics

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