Plazomicin - Achaogen

Drug Profile

Plazomicin - Achaogen

Alternative Names: [14C]-plazomicin; ACHN-490; Plazomicin sulfate; ZEMDRI

Latest Information Update: 24 Jul 2018

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Achaogen
  • Class Aminoglycosides; Antibacterials; Small molecules
  • Mechanism of Action Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Urinary tract infections
  • Registered Pyelonephritis
  • Preregistration Bacteraemia; Nosocomial pneumonia
  • Preclinical Gram-negative infections
  • No development reported Respiratory tract infections; Tularaemia; Yersinia infections

Most Recent Events

  • 27 Jun 2018 Registered for Pyelonephritis (Treatment-resistant) in USA (IV)- First Global Approval
  • 27 Jun 2018 Registered for Urinary tract infections (Treatment-resistant) in USA (IV)- First Global Approval
  • 26 Jun 2018 Achaogen receives complete response letter from the FDA for Plazomicin in Bloodstream infection
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