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Research programme: kinase inhibitors - Alexion AstraZeneca Rare Disease

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Drug Profile

Research programme: kinase inhibitors - Alexion AstraZeneca Rare Disease

Alternative Names: Dual SYK/JAK inhibitors - Alexion AstraZeneca Rare Disease; JAK programme - Alexion AstraZeneca Rare Disease; PRT 0318; PRT060318; PRT318; Syk kinase inhibitors - Biogen/Alexion AstraZeneca Rare Disease

Latest Information Update: 14 Feb 2022

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At a glance

  • Originator Portola Pharmaceuticals
  • Developer Alexion AstraZeneca Rare Disease; Portola Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Janus kinase 2 inhibitors; Janus kinase 3 inhibitors; Janus kinase inhibitors; Syk kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Eye disorders; Haematological malignancies; Inflammation
  • Discontinued Thrombosis

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Eye-disorders in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Haematological-malignancies in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Inflammation in USA (PO)

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