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Lacutamab - Innate Pharma/University of Genoa

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Drug Profile

Lacutamab - Innate Pharma/University of Genoa

Alternative Names: Anti-KIR3DL2 antibody; Anti-KIR3DL2 cytotoxic mAb; IPH 41; IPH4102

Latest Information Update: 04 Jun 2025

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At a glance

  • Originator University of Genoa
  • Developer Innate Pharma; Lymphoma Academic Research Organisation
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; KIR3DL2 receptor antagonists; Natural killer cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T-cell lymphoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Cutaneous T-cell lymphoma; Mycosis fungoides; Peripheral T-cell lymphoma; Sezary syndrome

Most Recent Events

  • 23 May 2025 Efficacy data from a phase-II trial in Sezary syndrome and Mycosis fungoides released by Innate Pharma
  • 23 May 2025 Innate Pharma plans a phase-III trial for Sezary syndrome and Mycosis fungoides
  • 28 Apr 2025 No recent reports of development identified for phase-I development in Peripheral-T-cell-lymphoma(Second-line therapy or greater) in South Korea (IV)

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