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SB 728 T

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Drug Profile

SB 728 T

Alternative Names: CCR5-ZFN; SB 728mR T; SB-728-modified-T-cells; SB-728-T; SB-728-T-CCR5-gene-therapy; ZFP Therapeutic

Latest Information Update: 29 May 2024

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At a glance

  • Originator Sangamo BioSciences
  • Developer Sangamo Therapeutics
  • Class Antivirals; Cell therapies; Gene therapies; T lymphocyte cell therapies; Zinc finger DNA binding proteins
  • Mechanism of Action T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - HIV infections

Highest Development Phases

  • Discontinued HIV infections

Most Recent Events

  • 28 Feb 2024 Case Western Reserve University completes the TRAILBLAZER phase I/II trial in HIV infections in USA (IV, Infusion) (NCT03666871)
  • 31 Dec 2020 Discontinued - Phase-II for HIV infections in USA, Puerto Rico (IV)
  • 12 Jun 2019 Case Western Reserve University initiates enrolment in the TRAILBLAZER phase I/II trial for HIV infections in USA (NCT03666871)

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