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Cabotegravir - ViiV Healthcare

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Drug Profile

Cabotegravir - ViiV Healthcare

Alternative Names: 1265744; 744 LA Injection; APRETUDE; Apretude; CAB LA - ViiV Healthcare; Cabotegravir long acting; Cabotegravir sodium; GSK-1265744; GSK-1265744A; GSK-1265744B; GSK-744; GSK-744-LA; GSK1265744 LAP; S-265744; S-265744B; S/GSK-1265744; S/GSK1265744 LAP

Latest Information Update: 12 Mar 2025

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At a glance

  • Originator Shionogi - GlaxoSmithKline (JV)
  • Developer Gilead Sciences; National Institute of Allergy and Infectious Diseases; ViiV Healthcare
  • Class Amides; Antiretrovirals; Fluorobenzenes; Oxazoles; Pyrazines; Pyridones; Small molecules
  • Mechanism of Action HIV integrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV infections
  • Registered HIV-1 infections

Most Recent Events

  • 17 Jan 2025 ViiV Healthcare initiates phase I pharmacokinetics trial in helathy volunteers in US (Injection) (NCT06786520)
  • 20 Dec 2024 Phase-II clinical trials in HIV infections (In adolescents, In adults, In the elderly, Prevention) in Puerto Rico and USA (IM) (NCT06741397)
  • 19 Dec 2024 ViiV Healthcare plans a phase IIb trial for HIV infections (In adolescents, In adults, In the elderly, Prevention) in Puerto Rico, USA (IM, Injection) (EudraCT2024-000061-24), (NCT06741397)

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