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Cabotegravir - ViiV Healthcare

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Drug Profile

Cabotegravir - ViiV Healthcare

Alternative Names: 1265744; 744 LA Injection; APRETUDE; Apretude; CAB LA - ViiV Healthcare; Cabotegravir long acting; Cabotegravir sodium; GSK-1265744; GSK-1265744A; GSK-1265744B; GSK-744; GSK-744-LA; GSK1265744 LAP; S-265744; S-265744B; S/GSK-1265744; S/GSK1265744 LAP

Latest Information Update: 28 May 2026

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At a glance

  • Originator Shionogi - GlaxoSmithKline (JV)
  • Developer Gilead Sciences; National Institute of Allergy and Infectious Diseases; ViiV Healthcare
  • Class Amides; Antiretrovirals; Fluorobenzenes; Oxazoles; Pyrazines; Pyridones; Small molecules
  • Mechanism of Action HIV integrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV infections
  • Registered HIV-1 infections

Most Recent Events

  • 15 Apr 2026 Phase-I/II clinical trials in HIV infections (In neonates, Prevention) in South Africa (IM) (NCT07275606)
  • 10 Dec 2025 ViiV Healthcare plans a phase I/II CABNATE trial for HIV Infections (In neonates) (PO, IM) in March 2026(NCT07275606 )
  • 15 Oct 2025 Efficacy and adverse events data from a phase I CLARITY trial (In volunteers) released by ViiV Healthcare

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