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Cabotegravir - ViiV Healthcare

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Drug Profile

Cabotegravir - ViiV Healthcare

Alternative Names: 1265744; 744 LA Injection; APRETUDE; Apretude; CAB LA - ViiV Healthcare; Cabotegravir long acting; Cabotegravir sodium; GSK-1265744; GSK-1265744A; GSK-1265744B; GSK-744; GSK-744-LA; GSK1265744 LAP; S-265744; S-265744B; S/GSK-1265744; S/GSK1265744 LAP

Latest Information Update: 23 Oct 2025

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At a glance

  • Originator Shionogi - GlaxoSmithKline (JV)
  • Developer Gilead Sciences; National Institute of Allergy and Infectious Diseases; ViiV Healthcare
  • Class Amides; Antiretrovirals; Fluorobenzenes; Oxazoles; Pyrazines; Pyridones; Small molecules
  • Mechanism of Action HIV integrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV infections
  • Registered HIV-1 infections

Most Recent Events

  • 15 Oct 2025 Efficacy and adverse events data from a phase I CLARITY trial (In volunteers) released by ViiV Healthcare
  • 22 Apr 2025 ViiV Healthcare initiates enrolment in a phase I trial for HIV infections (In volunteers, Prevention) in US (IM) (NCT06970223)
  • 31 Mar 2025 ViiV Healthcare completes a phase-II/III clinical trials in HIV infections (Prevention) in USA, Thailand, Argentina, Brazil, Peru, South Africa and Vietnam(IM) (NCT02720094)

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