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Cabotegravir injection - ViiV Healthcare

Drug Profile

Cabotegravir injection - ViiV Healthcare

Alternative Names: 1265744; 744 LA Injection; APRETUDE; Apretude; CAB LA - ViiV Healthcare; Cabotegravir long acting; Cabotegravir sodium; GSK-1265744; GSK-1265744A; GSK-1265744B; GSK-744; GSK-744-LA; GSK1265744 LAP; S-265744; S-265744B; S/GSK-1265744; S/GSK1265744 LAP

Latest Information Update: 22 Nov 2023

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At a glance

  • Originator Shionogi - GlaxoSmithKline (JV)
  • Developer Gilead Sciences; National Institute of Allergy and Infectious Diseases; ViiV Healthcare
  • Class Amides; Antiretrovirals; Fluorobenzenes; Oxazoles; Pyrazines; Pyridones; Small molecules
  • Mechanism of Action HIV integrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV infections
  • Registered HIV-1 infections

Most Recent Events

  • 22 Nov 2023 ViiV Healthcare plans the phase III PALISADE trial in HIV infections (In volunteers, In children, In adolescents, In adults, In the elderly) (IM) in January 2024 (NCT06134362)
  • 13 Sep 2023 ViiV Healthcare plans a phase I pharmacokinetic trial in healthy volunteer in USA (NCT06033547)
  • 28 Aug 2023 No recent reports of development identified for phase-I development in HIV-infections(Prevention) in New Zealand (IM, Injection)
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