Tomaralimab - Opsona Therapeutics

Drug Profile

Tomaralimab - Opsona Therapeutics

Alternative Names: Anti-TLR2 monoclonal antibody - Opsona Therapeutics; Anti-Toll-like receptor 2 monoclonal antibody - Opsona Therapeutics; OPN 305

Latest Information Update: 16 Apr 2018

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At a glance

  • Originator Opsona Therapeutics
  • Class Anti-inflammatories; Monoclonal antibodies
  • Mechanism of Action Toll like receptor 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Delayed graft function; Myelodysplastic syndromes
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Delayed graft function
  • Phase I/II Myelodysplastic syndromes
  • No development reported Autoimmune disorders; Inflammation

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 27 Feb 2018 Opsona Therapeutics initiates enrolment in a phase I/II follow up study of OPN-305-106 study for Myelodysplastic Syndrome (Second line therapy or greater) in Ireland (NCT03337451)
  • 16 Nov 2017 Opsona Therapeutics plans a phase I/II follow up study of OPN-305-106 study for Myelodysplastic Syndrome in Ireland (NCT03337451)
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