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Corticotropin - Mallinckrodt

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Drug Profile

Corticotropin - Mallinckrodt

Alternative Names: ACTH gel; Acthar; Acthar Gel therapy; Adrenocorticotropin gel - Mallinckrodt; H.P. Acthar Gel; Repository corticotropin injection - Mallinckrodt; SelfJect™

Latest Information Update: 13 Nov 2024

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At a glance

  • Originator Aventis Pharmaceuticals
  • Developer Mallinckrodt plc
  • Class Anterior pituitary hormones; Anti-inflammatories; Antiepileptic drugs; Antipsoriatics; Antirheumatics; Corticosteroids; Eye disorder therapies; Hypothalamic hormones; Urologics
  • Mechanism of Action Corticotropin receptor agonists; Steroid receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis; Infantile spasms
  • New Molecular Entity No

Highest Development Phases

  • Marketed Ankylosing spondylitis; Infantile spasms; Juvenile rheumatoid arthritis; Membranous glomerulonephritis; Multiple sclerosis; Nephrotic syndrome; Ocular inflammation; Polymyositis; Psoriatic arthritis; Rheumatoid arthritis; Sarcoidosis; Systemic lupus erythematosus
  • Phase II Scleritis
  • Discontinued Amyotrophic lateral sclerosis; Diabetic nephropathies

Most Recent Events

  • 13 Nov 2024 Discontinued - Phase-II for Amyotrophic lateral sclerosis in Mexico, Colombia, Canada, Chile, Argentina, Peru, USA (SC)
  • 06 Aug 2024 Mallinckrodt launches Corticotropin injector (SelfJect™) in Infantile spasms (In infants, In neonates), Multiple sclerosis, Sarcoidosis, Systemic lupus erythematosus, Nephrotic syndrome, Ocular inflammation, Psoriatic arthritis, Rheumatoid arthritis, Ankylosing spondylitis, Juvenile rheumatoid arthritis in USA
  • 09 May 2024 Mallinckrodt expects to launch Corticotropin injector (SelfJect) in the USA in the third quarter of 2024

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