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Roluperidone - Minerva Neurosciences/Mitsubishi Tanabe Pharma Corporation

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Drug Profile

Roluperidone - Minerva Neurosciences/Mitsubishi Tanabe Pharma Corporation

Alternative Names: CYR-101; MIN-101; MT-210

Latest Information Update: 07 May 2024

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At a glance

  • Originator Mitsubishi Tanabe Pharma Corporation
  • Developer Minerva Neurosciences
  • Class Antidementias; Antiparkinsonians; Antipsychotics; Behavioural disorder therapies; Fluorobenzenes; Isoindoles; Piperidines; Small molecules
  • Mechanism of Action Alpha-1a adrenergic receptor antagonists; Serotonin 2A receptor antagonists; Sigma-2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Schizophrenia
  • Preclinical Dementia
  • Research Alzheimer's disease; Parkinson's disease; Pervasive child development disorders

Most Recent Events

  • 01 May 2024 Pharmacokinetics and adverse events data from a phase I trial in Schizophrenia released by Minerva Neurosciences
  • 27 Feb 2024 Minerva Neurosciences receives complete response letter from the US FDA for roluperidone in Schizophrenia
  • 12 Jan 2024 Minerva Neurosciences completes the phase I trial in Schizophrenia in USA (NCT06107803)

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