Drug Profile

Nelitolimod - TriSalus Life Sciences

Alternative Names: ISS-ODN SD-101; SD-101; SD101-Dynavax

Latest Information Update: 02 Apr 2026

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At a glance

Originator Dynavax Technologies
Developer Bristol-Myers Squibb; Dynavax Technologies; Merck & Co; National Cancer Institute (USA); Stanford University School of Medicine; TriSalus Life Sciences; University of California, Davis
Class Antineoplastics; Antivirals; Immunotherapies; Oligodeoxyribonucleotides
Mechanism of Action Toll-like receptor 9 agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Phase II Prostate cancer
Phase I/II B-cell lymphoma; Cholangiocarcinoma; Follicular lymphoma; Head and neck cancer; Liver cancer; Lymphoma; Malignant melanoma
Phase I Pancreatic cancer; Uveal melanoma
Preclinical Colorectal cancer
No development reported Haematological malignancies; Hepatitis C; Solid tumours

18 Mar 2026 Pharmacodynamics and pharmacokinetics data from a preclinical study in Liver cancer released by TriSalus Life Sciences
10 Feb 2026 Dynavax Technologies has been acquired by Sanofi
13 Nov 2025 Nelitolimod - TriSalus Life Sciences is available for licensing as of 13 Nov 2025. https://trisaluslifesci.com/contact/

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