REC 4881
Alternative Names: REC-4881; TAK-733Latest Information Update: 23 Aug 2024
At a glance
- Originator Exscientia; Takeda
- Developer Recursion Pharmaceuticals
- Class Antineoplastics; Small molecules
- Mechanism of Action MAP kinase kinase 1 inhibitors; MAP kinase kinase 2 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Familial adenomatous polyposis; Solid tumours
- Discontinued Non-small cell lung cancer
Most Recent Events
- 08 Aug 2024 Recursion Pharmaceuticals and Exscientia agree to co-promote and co-develop REC 4881 for familial adenomatous polyposis
- 15 Jan 2024 Phase-II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT06005974)
- 08 Aug 2023 Recursion Pharmaceuticals plans a phase II trial in Solid tumours (Inoperable/Unresectable, Late stage disease, Metastatic disease) in Q4 of 2023