Drug Profile


Alternative Names: 423; AAT-007; ARY 007; CJ-023; CJ-023,423; CJ-23423; MR-10A7; RQ-00000007; RQ-7

Latest Information Update: 27 Jul 2018

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At a glance

  • Originator Pfizer
  • Developer AskAt; Kyn Therapeutics; Maruishi Pharmaceutical
  • Class Analgesics; Anti-inflammatories; Antiallergics; Antineoplastics; Antirheumatics; Benzene derivatives; Imidazoles; Pyridines; Small molecules; Sulfonamides; Sulfonylureas
  • Mechanism of Action Epidermal growth factor inhibitors; Interleukin 23 inhibitors; Interleukin 6 inhibitors; Interleukin-17 inhibitors; Prostaglandin E EP4 receptor antagonists; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer
  • No development reported Acute pain; Autoimmune disorders; Cancer pain; Hypersensitivity; Inflammation; Postoperative pain

Most Recent Events

  • 05 Feb 2018 Kyn Therapeutics plans a phase Ib trial for cancer
  • 14 Dec 2017 Preclinical trials in Cancer in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Acute pain in Japan (IV)
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