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MIS 416

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Drug Profile

MIS 416

Alternative Names: MIS-416

Latest Information Update: 28 Dec 2022

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At a glance

  • Originator Virionyx
  • Developer Amplia Therapeutics Limited; Innate Immunotherapeutics
  • Class Adjuvants; Anti-infectives; Antineoplastics; Neuroprotectants
  • Mechanism of Action Immunomodulators; Immunostimulants; NOD2 protein agonists; NOD2 protein modulators; Toll-like receptor 9 agonists; Toll-like receptor 9 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cancer; Infections; Multiple sclerosis; Solid tumours

Most Recent Events

  • 28 Dec 2022 Discontinued - Phase-I for Solid tumours (Combination therapy, Second-line therapy or greater) in Japan (Parenteral) (Amplia Therapeutics pipeline, December 2022)
  • 28 Dec 2022 Discontinued - Preclinical for Cancer in New Zealand (Parenteral) (Amplia Therapeutics pipeline, December 2022)
  • 28 Dec 2022 Discontinued - Preclinical for Infections in New Zealand (Parenteral) (Amplia Therapeutics pipeline, December 2022)

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