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Leukocyte cell therapy - Enlivex Therapeutics

Drug Profile

Leukocyte cell therapy - Enlivex Therapeutics

Alternative Names: Allocetra; Allocetra-OTS; ApoCell; Haematopoitetic-stem-cell-therapy-Enlivex-Therapeutics; OTS-Allocetra

Latest Information Update: 29 Nov 2019

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At a glance

  • Originator Hadassah Medical Organization
  • Developer Enlivex Therapeutics; Hadassah Medical Organization
  • Class Anti-infectives; Anti-inflammatories; Cell therapies
  • Mechanism of Action Cell replacements; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Graft-versus-host disease
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Graft-versus-host disease; Inflammation
  • Phase I Multiple organ failure
  • Preclinical Gout; Multiple sclerosis; Rheumatoid arthritis; Solid tumours
  • No development reported Crohn's disease; Transplant rejection

Most Recent Events

  • 18 Nov 2019 Enlivex Therapeutics completes enrolment in its phase Ib P-SOFA-1 trial for Severe sepsis in Israel (NCT03925857)
  • 04 Nov 2019 Interim adverse events and efficacy data from a phase I clinical trials in Multiple organ failure released by Enlivex Therapeutics
  • 10 Oct 2019 Pharmacodynamics data from a preclinical trial in Multiple organ failure released by Enlivex Therapeutics
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