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Leukocyte cell therapy - Enlivex Therapeutics

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Drug Profile

Leukocyte cell therapy - Enlivex Therapeutics

Alternative Names: Allocetra; Allocetra-OTS; OTS-Allocetra

Latest Information Update: 14 Jun 2025

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At a glance

  • Originator Hadassah Medical Organization
  • Developer Enlivex Therapeutics; Hadassah Medical Organization
  • Class Antineoplastics; Cell therapies; Immunotherapies
  • Mechanism of Action Leukocyte replacements; Macrophage modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Graft-versus-host disease
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Graft-versus-host disease; Inflammation; Lung disorders; Multiple organ failure; SARS-CoV-2 acute respiratory disease
  • Phase I/II Osteoarthritis
  • Phase I Psoriatic arthritis
  • No development reported Crohn's disease; Gout; Multiple sclerosis; Rheumatoid arthritis; Transplant rejection
  • Discontinued COVID 2019 infections; Mesothelioma; Peritoneal cancer; Solid tumours

Most Recent Events

  • 21 Apr 2025 Enlivex Therapeutics completes enrolment phase-I/II clinical trials in Osteoarthritis (Treatment-experienced, In adults, In the elderly) in Denmark, Israel and Moldova (Intra-articular) (NCT06233474)
  • 03 Apr 2025 Enlivex Therapeutics initiates a phase I clinical trials in Osteoarthritis in Israel
  • 03 Mar 2025 Efficacy and adverse event data from a phase I/II trial in Osteoarthritis released by Enlivex Therapeutics

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