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Sotagliflozin - Lexicon Pharmaceuticals

Drug Profile

Sotagliflozin - Lexicon Pharmaceuticals

Alternative Names: INPEFA; LP-802034; LX-4211; SAR 439954; Zynquista

Latest Information Update: 03 Jun 2024

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At a glance

  • Originator Lexicon Pharmaceuticals
  • Developer Lexicon Pharmaceuticals; Sanofi
  • Class Alcohols; Antihyperglycaemics; Chlorobenzenes; Glycosides; Heart failure therapies; Phenyl ethers; Pyrans; Small molecules; Sulfhydryl compounds
  • Mechanism of Action Sodium-glucose transporter 1 inhibitors; Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Heart failure; Type 2 diabetes mellitus
  • Registered Type 1 diabetes mellitus

Most Recent Events

  • 03 Jun 2024 Adverse events data from a phase III trial in Type II diabetes mellitus and Renal failure presented at the 73rd Annual Scientific Session of the American College of Cardiology (ACC-2024)
  • 02 May 2024 Lexicon plans a phase III trial for Hypertrophic cardiomyopathy and expects to begin enrollment in the middle of the year 2024
  • 29 Apr 2024 Lexicon Pharmaceuticals announces intention to launch sotagliflozin for hypertrophic cardiomyopathy by late 2027
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