Sotagliflozin - Lexicon Pharmaceuticals
Alternative Names: INPEFA; LP-802034; LX-4211; SAR 439954; ZynquistaLatest Information Update: 22 Jul 2024
At a glance
- Originator Lexicon Pharmaceuticals
- Developer Lexicon Pharmaceuticals; Sanofi
- Class Alcohols; Antihyperglycaemics; Chlorobenzenes; Glycosides; Heart failure therapies; Phenyl ethers; Pyrans; Small molecules; Sulfhydryl compounds
- Mechanism of Action Sodium-glucose transporter 1 inhibitors; Sodium-glucose transporter 2 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Heart failure; Type 2 diabetes mellitus
- Registered Type 1 diabetes mellitus
- Phase III Hypertrophic cardiomyopathy
Most Recent Events
- 16 Jul 2024 The US FDA sets PDUFA date of December 2024 for NDA review of sotagliflozin for for type 1 diabetes and chronic kidney disease
- 16 Jul 2024 US FDA accepts the resubmission of NDA for sotagliflozin for type 1 diabetes and chronic kidney disease for review
- 28 Jun 2024 Phase-III clinical trials in Hypertrophic cardiomyopathy in USA (PO) (NCT06481891)