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Daprodustat - GSK

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Drug Profile

Daprodustat - GSK

Alternative Names: 1278863; Duvroq; GSK-1278863; GSK-1278863A; Jesduvroq

Latest Information Update: 23 Sep 2024

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At a glance

  • Originator GlaxoSmithKline
  • Developer GSK
  • Class Acetic acids; Amides; Anti-ischaemics; Antianaemics; Cyclohexanes; Foot disorder therapies; Ketones; Pyrimidines; Skin disorder therapies; Small molecules; Vascular disorder therapies
  • Mechanism of Action Hypoxia-inducible factor-proline dioxygenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Anaemia
  • Discontinued Diabetic foot ulcer; Perioperative ischaemia; Peripheral arterial disorders; Tendon injuries

Most Recent Events

  • 13 Jun 2024 Pharmacodynamics data from a preclinical trial in Anaemia presented at the 29th Congress of the European Haematology Association (EHA-2024)
  • 06 Sep 2023 Phase-III clinical trials in Anaemia (In infants, In children, In adolescents) in United Kingdom, USA, Turkey, Poland, Spain, Netherlands, Japan, South Korea, Italy, Germany, France, Canada, Belgium, Austria and Argentina (PO) (NCT05682326)
  • 22 Jul 2023 CHMP recommends approval of Daprodustat for Anaemia in EU

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