Mannitol/proline - DNage

Drug Profile

Mannitol/proline - DNage

Alternative Names: D-mannitol/L-proline - DNage; Prodarsan

Latest Information Update: 12 May 2014

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At a glance

  • Originator DNage
  • Class Amino acids; Small molecules; Sugar alcohols
  • Mechanism of Action Antioxidants; Free radical scavengers; Oxygen radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cockayne syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cockayne syndrome

Most Recent Events

  • 31 Jan 2011 Discontinued - Phase-I for Cockayne syndrome in Netherlands (PO)
  • 31 Jan 2011 Discontinued - Preclinical for Cockayne syndrome in USA (PO)
  • 19 Jul 2010 DNage is no longer a wholly-owned subsidiary of Pharming Group
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