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Viagenpumatucel-L - NightHawk Biosciences/University of Miami

Drug Profile

Viagenpumatucel-L - NightHawk Biosciences/University of Miami

Alternative Names: Ad100-gp96Ig-HLA A1; Gp96-Ig and HLA A1 transfected Non-Small Cell Lung Cancer cell line; gp96-Ig lung cancer vaccine - NightHawk Biosciences /University of Miami; HS-110; HS-L1

Latest Information Update: 08 Apr 2023

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At a glance

  • Originator University of Miami
  • Developer NightHawk Biosciences
  • Class Antineoplastics; Cancer vaccines; Immunotherapies
  • Mechanism of Action Heat-shock protein stimulants; Immunostimulants; OX40 ligand stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 31 Mar 2023 Discontinued - Phase-I for Solid tumours (Combination therapy, In the elderly, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent, In adults) in USA (Intradermal) (before March 2023)
  • 31 Mar 2023 Discontinued - Phase-II for Non-small cell lung cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Intradermal) (before March 2023)
  • 01 Jan 2023 NightHawk Biosciences terminates its licensing agreement with University of Miami for gp96 and TNFRSF25 platforms
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