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Research programme: BET inhibitors - Zenith Epigenetics

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Drug Profile

Research programme: BET inhibitors - Zenith Epigenetics

Alternative Names: NexVas Autoimmune (AI) programme - Resverlogix; NexVas vascular inflammation; NexVas VI (vascular inflammation) therapy - Resverlogix; RVX-297; ZEN-3118; ZEN-3212; ZEN-3228; ZEN-3293; ZEN-3309; ZEN2135; ZEN222; ZEN297; ZEN3317

Latest Information Update: 22 Feb 2023

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At a glance

  • Originator Resverlogix Corporation; Zenith Epigenetics
  • Developer Zenith Epigenetics
  • Class Small molecules
  • Mechanism of Action BRD4 protein inhibitors; Bromodomain and extraterminal domain protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Autoimmune disorders; Cancer

Most Recent Events

  • 22 Feb 2023 Discontinued - Preclinical for Autoimmune disorders in Canada (PO)
  • 22 Feb 2023 Discontinued - Preclinical for Cancer in Canada (PO)
  • 28 Oct 2018 No recent reports of development identified for preclinical development in Cancer in Canada (PO)

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