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Padeliporfin - ImPact Biotech

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Drug Profile

Padeliporfin - ImPact Biotech

Alternative Names: Padeliporfin di-potassium - ImPact Biotech; Padeliporfin ImPACT; Padeliporfin VTP; Palladium bacteriopheophorbide monolysine taurine; Stakel; TOOKAD Soluble; WST-11

Latest Information Update: 10 Dec 2024

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At a glance

  • Originator Steba Laboratories
  • Developer ImPact Biotech
  • Class Antineoplastics; Eye disorder therapies; Porphyrins; Small molecules
  • Mechanism of Action Photosensitisers; Vascular disrupting agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer; Urogenital cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Prostate cancer
  • Phase III Urogenital cancer
  • Phase I/II Renal cancer
  • Phase I Adenocarcinoma; Lung cancer; Oesophageal cancer
  • Preclinical Degenerative myopia; Non-small cell lung cancer; Pancreatic cancer
  • Suspended Choroidal neovascularisation
  • No development reported Cholangiocarcinoma

Most Recent Events

  • 04 Dec 2024 Updated efficacy and adverse event data from phase III ENLIGHTED trial in Urogenital cancer released by ImPact Biotech
  • 07 Nov 2024 Efficacy and adverse event data from phase III ENLIGHTED trial in Urogenital cancer released by ImPact Biotech
  • 30 Oct 2024 Phase-I clinical trials in Lung cancer in USA (IV) (NCT05918783)

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