tgAAG 76

Drug Profile

tgAAG 76

Alternative Names: AAV-RPE65; Leber's hereditary optic atrophy gene therapy - AmpliPhi Biosciences; rAAV2/2.hRPE65p.hRPE65; RPE65 gene therapy - AmpliPhi Biosciences; tgAAG76

Latest Information Update: 10 Oct 2017

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At a glance

  • Originator Targeted Genetics Corporation
  • Developer AmpliPhi Biosciences Corporation; University College London
  • Class Gene therapies
  • Mechanism of Action Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Leber's hereditary optic atrophy

Most Recent Events

  • 08 Apr 2011 Genzyme Corporation has been acquired by sanofi-aventis
  • 09 Mar 2011 Targeted Genetics Corporation is now called AmpliPhi Biosciences
  • 11 Nov 2010 Phase I/II development is ongoing in United Kingdom
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