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Entolimod - Cleveland BioLabs

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Drug Profile

Entolimod - Cleveland BioLabs

Alternative Names: CBLB 502

Latest Information Update: 28 Aug 2018

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At a glance

  • Originator Cleveland BioLabs
  • Class Anti-ischaemics; Antidotes; Antineoplastics; Chemoprotectants; Peptides; Radioprotectives; Recombinant proteins
  • Mechanism of Action Apoptosis inhibitors; NF-kappa B modulators; Toll-like receptor 5 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute radiation syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Colorectal cancer
  • No development reported Acute radiation syndrome; Cancer; Radiation injuries; Reperfusion injury

Most Recent Events

  • 28 Aug 2018 No recent reports of development identified for phase-I development in Acute-radiation-syndrome in USA (IM, Injection)
  • 28 Aug 2018 No recent reports of development identified for phase-I development in Cancer(Inoperable/Unresectable, Late-stage disease) in Russia (IM, Injection)
  • 28 Aug 2018 No recent reports of development identified for phase-I development in Cancer(Inoperable/Unresectable, Late-stage disease) in USA (IM, Injection)
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