NT 503

Drug Profile

NT 503

Alternative Names: Encapsulated VEGF inhibitor - Neurotech; NT-503; NT-503-2; NT-503-3; Wet AMD encapsulated cell therapy - Neurotech

Latest Information Update: 18 Oct 2016

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At a glance

  • Originator Neurotech USA
  • Class Cell therapies; Eye disorder therapies
  • Mechanism of Action Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Choroidal neovascularisation

Most Recent Events

  • 18 Oct 2016 Neurotech USA terminates phase II portion of a phase I/II trial in Choroidal neovascularisation (Recurrent, Treatment-experienced) in USA and Israel (Neurotech USA pipeline, July 2016)
  • 30 Mar 2015 Phase-II clinical trials in Choroidal neovascularisation (Recurrent, Treatment-experienced) in Israel (Intraocular) (NCT02228304)
  • 30 Mar 2015 US FDA approves IND application for NT 503 3 in Choroidal neovascularisation
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