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Bryostatin analogues - Aphios Corporation

Drug Profile

Bryostatin analogues - Aphios Corporation

Alternative Names: APH-0703; APH-1104; Bryosomes; Bryostatin 1-containing phospholipid nanosomes (Bryosomes™) - Aphios; Nanoencapsulated APH 0703

Latest Information Update: 28 Jan 2024

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At a glance

  • Originator Aphios Corporation
  • Developer Aphios Corporation; Louisiana State University; University Hospital Muenster
  • Class Antidementias; Antineoplastics; Lactones; Macrocyclic compounds; Nootropics
  • Mechanism of Action Amyloid beta-protein inhibitors; Protein kinase C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Alzheimer's disease; Cognition disorders
  • No development reported Down syndrome; Reperfusion injury
  • Discontinued Oesophageal cancer

Most Recent Events

  • 28 Jan 2024 No recent reports of development identified for preclinical development in Down syndrome in USA (PO)
  • 28 Apr 2023 No recent reports of development identified for preclinical development in Reperfusion-injury in Germany
  • 28 Apr 2023 No recent reports of development identified for preclinical development in Reperfusion-injury in USA
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