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BNC 210

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Drug Profile

BNC 210

Alternative Names: BNC-210; IW 2143

Latest Information Update: 30 Oct 2025

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At a glance

  • Originator Bionomics
  • Developer Bionomics; EmpathBio
  • Class Antidepressants; Anxiolytics; Behavioural disorder therapies; Small molecules
  • Mechanism of Action Alpha7 nicotinic acetylcholine receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Anxiety disorders
  • Phase II Agitation; Post-traumatic stress disorders
  • No development reported Depressive disorders

Most Recent Events

  • 21 Oct 2025 Neuphoria Therapeutics plans to evaluate next steps for further development of BNC 210 in post-traumatic stress disorder
  • 29 Sep 2025 Neuphoria Therapeutics plans to initiate the phase IIb/III SYMPHONY trial in Post-traumatic stress disorder (PO) in the first half of 2026
  • 20 May 2025 Neuphoria Therapeutics completes an end of phase II meeting with the US FDA for a phase IIb (SYMPHONY) trials in Post traumatic stress disorders

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