Drug Profile


Alternative Names: BI-10773/metformin; Empagliflozin/metformin extended-release; Empagliflozin/metformin immediate-release; Gibtulio Met; Metformin/BI-10773; Metformin/empagliflozin; Metformin/empagliflozin extended-release; Metformin/empagliflozin immediate-release; Metformin/empagliflozin XR; Synjardy; Synjardy XR

Latest Information Update: 20 Aug 2018

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At a glance

  • Originator Boehringer Ingelheim
  • Developer Boehringer Ingelheim; Eli Lilly
  • Class Antihyperglycaemics; Benzhydryl compounds; Biguanides; Cyclic ethers; Glucosides; Small molecules
  • Mechanism of Action AMP activated protein kinase stimulants; Gluconeogenesis inhibitors; Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Type 2 diabetes mellitus

Most Recent Events

  • 15 Aug 2018 Depomed is now called Assertio Therapeutics
  • 11 Jul 2018 Boehringer Ingelheim and Lupin agree to market empagliflozin/metformin in India for Type-2 diabetes mellitus
  • 02 Jul 2018 CHMP issues positive opinion to expand the empagliflozin/metformin label to include positive effects on cardiovascular and renal outcomes in the European Union
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