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Alternative Names:
HY-13328; INK-128; MLN-0128; TAK-228
Latest Information Update: 15 Sep 2020
Price :
$50
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At a glance
Originator
Intellikine
Developer
Dana-Farber Cancer Institute; European Network for Translational Research in Ovarian Cancer (EUTROC); M. D. Anderson Cancer Center; National Cancer Institute (USA); Takeda; Takeda Oncology
Class
Antineoplastics; Benzoxazoles; Pyrazolones; Pyrimidines; Small molecules
Mechanism of Action
MTORC1 protein inhibitors; MTORC2 protein inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
18 Jun 2020
Phase-I clinical trials in Non-small cell lung cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater, Combination therapy) in USA (PO) (NCT04479306)
29 May 2020
Efficacy and safety data from a phase I/II trial in Sarcoma presented at the 56th Annual Meeting of the American Society of Clinical Oncology (ASCO-2020)
29 May 2020
Efficacy and adverse events data from a phase I trial in Solid tumours (Combination therapy) presented at the 56th Annual Meeting of the American Society of Clinical Oncology (ASCO-2020)
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