PRM 151

Drug Profile

PRM 151

Alternative Names: PRM-151; rhPTX 2; rhSAP; SAP; Serum amyloid P

Latest Information Update: 10 Jul 2018

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At a glance

  • Originator Promedior
  • Class Anti-inflammatories; Antifibrotics; Glycoproteins; Recombinant proteins
  • Mechanism of Action Transforming growth factor beta1 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Scars; Myelofibrosis; Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Idiopathic pulmonary fibrosis; Myelofibrosis; Scars
  • Preclinical Lung disorders
  • No development reported Kidney disorders

Most Recent Events

  • 02 Jul 2018 Efficacy data from a phase II trial in Idiopathic pulmonary fibrosis released by Promedior
  • 07 Dec 2016 Phase-II clinical trials in Myelofibrosis in Netherlands (IV), United Kingdom (IV), Germany (IV), Italy (IV), Israel (IV), France (IV) (NCT01981850)
  • 02 Dec 2016 Promedior completes enrolment in the phase II trial for Idiopathic pulmonary fibrosis in USA, Netherland, Germany, Belgium, Czech Republic, Spain, Italy, Switzerland and Hungary (NCT02550873) (EudraCT2014-004782-2)
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