Volixibat - Shire

Drug Profile

Volixibat - Shire

Alternative Names: LUM002; SAR-548304; SHP626; Volixibat potassium

Latest Information Update: 08 Aug 2018

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At a glance

  • Originator sanofi-aventis
  • Developer Sanofi; Shire
  • Class Antihyperlipidaemics; Benzothiepins; Hepatoprotectants; Urea compounds
  • Mechanism of Action Sodium-bile acid cotransporter-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cholestasis; Hypercholesterolaemia; Non-alcoholic steatohepatitis

Most Recent Events

  • 30 Jun 2018 Discontinued - Phase-II for Non-alcoholic steatohepatitis in USA, United Kingdom, Canada (PO)
  • 24 Jun 2018 Biomarkers information updated
  • 02 Feb 2017 Phase-II clinical trials in Non-alcoholic steatohepatitis in Canada (PO) (NCT02787304)
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