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Research programme: HDAC6 inhibitors - Celgene

Drug Profile

Research programme: HDAC6 inhibitors - Celgene

Alternative Names: ACY 1083; ACY-738

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Dana-Farber Cancer Institute; Harvard University
  • Developer Acetylon Pharmaceuticals; Celgene Corporation
  • Class Small molecules
  • Mechanism of Action HDAC6 protein inhibitors; Histone deacetylase inhibitors; Interleukin 10 inhibitors; Programmed cell death 1 ligand 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Charcot-Marie-Tooth disease; Chronic lymphocytic leukaemia
  • No development reported Autoimmune disorders; Cardiovascular disorders; Depressive disorders; Diabetes mellitus; Haematological malignancies; Neurological disorders; Stroke

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Cardiovascular-disorders in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Depressive disorders in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Diabetes-mellitus in USA (PO)
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