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AAB 003

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Drug Profile

AAB 003

Alternative Names: AAB-003; PF-05236812; PF-5236812

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Elan Corporation; Wyeth
  • Developer JANSSEN Alzheimer Immunotherapy; Pfizer
  • Class Antibodies; Antidementias; Monoclonal antibodies
  • Mechanism of Action Amyloid beta-protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alzheimer's disease

Most Recent Events

  • 06 Nov 2014 Discontinued - Phase-I for Alzheimer's disease in USA and South Korea (IV)
  • 31 Aug 2014 Pfizer & JANSSEN Alzheimer Immunotherapy complete a phase I trial for Alzheimer's disease in USA & South Korea (NCT01369225)
  • 12 Dec 2013 Pfizer & JANSSEN Alzheimer Immunotherapy suspend enrolment in a phase I extension trial for Alzheimer's disease in USA and South Korea (NCT01369225)

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