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Sevuparin - Modus Therapeutics

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Drug Profile

Sevuparin - Modus Therapeutics

Alternative Names: DF-02; Low anticoagulant heparin - Modus Therapeutics

Latest Information Update: 21 Mar 2025

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At a glance

  • Originator Dilafor
  • Developer Arabian Gulf University; Imperial College of Science, Technology and Medicine; Mahidol Oxford Tropical Medicine Research Unit; Modus Therapeutics
  • Class Anti-infectives; Anti-inflammatories; Antianaemics; Anticoagulants; Antimalarials; Antithrombotics; Heparins; Low molecular weight heparins; Polysaccharides; Urologics
  • Mechanism of Action Cell adhesion molecule inhibitors; E-selectin inhibitors; Fibronectin receptor antagonists; L-selectin inhibitors; P selectin inhibitors; Thrombospondin antagonists; Von Willebrand factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Anaemia; Falciparum malaria; Renal failure; Vaso-occlusive crisis
  • Phase I Sepsis
  • Preclinical Kidney disorders

Most Recent Events

  • 11 Mar 2025 Modus Therapeutics completes enrolment in its phase I trial in Falciparum malaria (Adjunctive treatment, In infants, In children) in Zambia and Kenya (IV) (ISRCTN32271864)
  • 09 Dec 2024 Phase-II clinical trials in Anaemia (unspecified route) in Italy
  • 09 Dec 2024 Phase-II clinical trials in Renal failure (unspecified route) in Italy

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