Rasdegafusp alfa

Drug Profile

Rasdegafusp alfa

Alternative Names: CDX-1401; DEC-205/NY-ESO-1 vaccine - Celldex

Latest Information Update: 17 May 2018

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At a glance

  • Originator Ludwig Institute for Cancer Research
  • Developer Celldex Therapeutics Inc; National Cancer Institute (USA); Roswell Park Cancer Institute
  • Class Cancer vaccines; Monoclonal antibodies; Recombinant fusion proteins
  • Mechanism of Action DEC-205 receptor agonists; Dendritic cell stimulants; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Fallopian tube cancer; Gynaecological cancer; Malignant melanoma; Myelodysplastic syndromes; Ovarian cancer; Peritoneal cancer; Solid tumours

Most Recent Events

  • 17 May 2018 Discontinued - Phase-I for Acute myeloid leukaemia (Combination therapy, Second-line therapy or greater) in USA (SC)
  • 17 May 2018 Discontinued - Phase-I for Myelodysplastic syndromes (Combination therapy, Second-line therapy or greater) in USA (SC)
  • 17 May 2018 Discontinued - Phase-I/II for Fallopian tube cancer (Combination therapy, Second-line therapy or greater) in USA (SC)
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