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Cendakimab - Celgene Corporation

Drug Profile

Cendakimab - Celgene Corporation

Alternative Names: ABT-308; BMS-986355; CC 93538; RPC 4046

Latest Information Update: 22 May 2025

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At a glance

  • Originator Abbott Laboratories
  • Developer AbbVie; Celgene Corporation
  • Class Anti-inflammatories; Antiasthmatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin 13 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Eosinophilic oesophagitis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Eosinophilic gastroenteritis; Eosinophilic oesophagitis
  • Phase II Atopic dermatitis; Systemic lupus erythematosus
  • Discontinued Asthma

Most Recent Events

  • 22 May 2025 Pooled pharmacokinetics and adverse events data from two phase I trials presented at the 32nd United European Gastroenterology Week (UEG-2024)
  • 11 Oct 2024 Celgene completes a phase I trial in Eosinophilic oesophagitis (Treatment-experienced) in USA (Parenteral) (NCT05175352)
  • 29 Aug 2024 Celgene completes a phase III trial in Eosinophilic oesophagitis (In adolescents, In children, In the elderly, In adults) in US, Germany, Argentina, Australia Italy Japan, Poland, Portugal, Austria, Belgium, Canada, Israel, Spain and United Kingdom and Switzerland (SC, Injection) (NCT04753697)

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