Research programme: monoclonal antibody-based therapeutics - Compugen

Drug Profile

Research programme: monoclonal antibody-based therapeutics - Compugen

Alternative Names: Antibody-based cancer immunotherapies - Compugen; Cancer immunotherapies - Compugen; CGEN 15027-targeted mAb; CGEN 15027-targeted monoclonal antibody; CGEN 15032-targeted immunotherapeutic; CGEN 15052-targeted mAb; CGEN 15052-targeted monoclonal antibody; CGEN 15137-targeted antibody; CGEN 15137/TIGIT; CGEN 671-targeted mAb; CGEN 671-targeted monoclonal antibody; CGEN XXXX; CGEN-15022-targeted mAb; CGEN-15022-targeted monoclonal antibody; CGEN-15049-targeted mAb; CGEN-15049-targeted monclonal antibody; CGEN-928-targeted mAb; CGEN-928-targeted monoclonal antibody; COM 902; COM902/TIGIT; Immune checkpoint-targeted monoclonal antibodies - Compugen; Splice variant-targeted monoclonal antibody therapeutics - Compugen

Latest Information Update: 10 Nov 2017

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At a glance

  • Originator Compugen
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action B7 antigen inhibitors; CD28 antigen inhibitors; Immunomodulators; Membrane protein inhibitors; TIGIT protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Solid tumours
  • Research Malignant melanoma
  • No development reported Haematological malignancies; Multiple myeloma

Most Recent Events

  • 26 Mar 2018 Compugen plans a clinical trial of COM 902 for Cancer in 2019
  • 06 Nov 2017 Compugen enters into a process development and manufacturing service agreement with Bayer HealthCare for COM 902
  • 06 Nov 2017 Compugen announces intention to submit IND for COM 902 to US FDA in 2019
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