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Naldemedine - Shionogi

Drug Profile

Naldemedine - Shionogi

Alternative Names: Rizmoic; S-297995; Symproic

Latest Information Update: 14 Mar 2021

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At a glance

  • Originator Shionogi
  • Developer Purdue Pharma; Shionogi
  • Class Antiemetics; Laxatives; Small molecules
  • Mechanism of Action Opioid mu receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Constipation
  • Phase II Postoperative ileus

Most Recent Events

  • 04 Jan 2021 Shionogi terminates a phase-II clinical trial in Postoperative ileus (In the elderly, In adults) due to slow patient enrollments, in USA (PO) (NCT04355169)
  • 01 Sep 2020 Phase-II clinical trials in Postoperative ileus (In the elderly, In adults) in USA (PO) (NCT04355169)
  • 23 Apr 2020 Shionogi plans a phase II trial for Postoperative ileus in USA (In adults, In the elderly) (PO), in May 2020 (NCT04355169 )
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