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Naldemedine - Shionogi

Drug Profile

Naldemedine - Shionogi

Alternative Names: Rizmoic; S-297995; Symproic

Latest Information Update: 24 Jun 2019

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At a glance

  • Originator Shionogi
  • Developer Purdue Pharma; Shionogi
  • Class Antiemetics; Small molecules
  • Mechanism of Action Opioid mu receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Constipation

Most Recent Events

  • 19 Jun 2019 Shionogi and Ferrer enters a marketing agreement for naldemedine for opioid-induced constipation in Spain
  • 22 May 2019 Naldemedine licensed to Molteni Therapeutics in Italy and Poland
  • 17 Apr 2019 Shionogi plans to initiate a clinical study of Naldemedine in paediatric patients with opioid-induced constipation in EU, in accordance with paediatric investigation plan
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